A dia­gno­stic instru­ment like no other — uni­ver­sal­ly appli­ca­ble, cli­ni­cal­ly vali­da­ted, award-winning

VASCASSIST: A dia­gno­stic tool like no other

Uni­ver­sal­ly appli­ca­ble, cli­ni­cal­ly vali­da­ted, award-winning

The num­e­rous appli­ca­ti­ons of Model-based Pul­se Wave Ana­ly­sis (mbPWA) have long been well known among experts: They are based on the enorm­ous per­for­mance of the algo­rithm-based mea­su­re­ment prin­ci­ple. Its strength lies not only in the unsur­pas­sed accu­ra­cy, but also scores with the hig­hest relia­bi­li­ty due to the repro­du­ci­bi­li­ty of the deter­mi­ned values.

The uni­que sel­ling point of Model-based Pul­se Wave Ana­ly­sis (mbPWA) pro­ves its­elf time and again not only in the dai­ly rou­ti­ne of gene­ral medi­cal and spe­cia­list care but also in par­ti­cu­lar in the con­text of cli­ni­cal stu­dies: The wide varie­ty of mea­sura­ble and cli­ni­cal­ly rele­vant para­me­ters forms a valuable data basis for the most diver­se sci­en­ti­fic questions.

The cor­ner­stone of validation

The dia­gno­stic advan­ta­ges of auto­ma­ted mea­su­re­ments with VASCASSIST have been repea­ted­ly con­firm­ed in cli­ni­cal trials.

The peri­phe­ral mea­su­re­ment to detect dan­ge­rous steno­ses in arms and legs was vali­da­ted by Saar­land Uni­ver­si­ty in 2016. In the fol­lo­wing year rese­ar­chers at the Uni­ver­si­ty of Hei­del­berg accre­di­ted the cen­tral pres­su­re mea­su­re­ment, tar­ge­ting aor­tic para­me­ters, thus aimed at the ear­ly detec­tion of car­dio­vas­cu­lar diseases.

The aor­tic pres­su­re stu­dy at Hei­del­berg Uni­ver­si­ty, led by PD Dr. med. Fre­de­ric Trink­mann: “Auto­ma­ted non-inva­si­ve cen­tral blood pres­su­re mea­su­re­ments using oscil­lo­me­tric radi­al pul­se wave ana­ly­sis — results of the MEA­SU­RE-cBP vali­da­ti­on stu­dies” won the Kurt and Eri­ka Palm Sci­ence Pri­ze of the Ger­man Heart Foundation,<//a> award­ed for the first time that year and joint­ly with the Ger­man Socie­ty for Pre­ven­ti­on and Reha­bi­li­ta­ti­on of Car­dio­vas­cu­lar Dise­a­ses (DGPR).

The first paper intro­du­cing Model-based Pul­se Wave Ana­ly­sis (mbPWA) as a new approach to car­dio­vas­cu­lar dia­gno­stics appeared in Janu­ary 2018, titled “Mul­ti­ple cou­pled reso­nan­ces in the human vas­cu­lar tree: refi­ning the Wes­ter­hof model of the arte­ri­al sys­tem,” in the Jour­nal of Appli­ed Phy­sio­lo­gy: https://doi.org/10.1152/japplphysiol.00405.2017.

List of publications

  • Mass­mann, Stem­ler et al., Saar­land Uni­ver­si­ty, Auto­ma­ted oscil­lo­me­tric blood pres­su­re and pul­se-wave acqui­si­ti­on for eva­lua­ti­on of vas­cu­lar stiff­ness in atheros­cle­ro­sis, Clin Res, Car­di­ol, 2017 https://doi.org/10.1007/s00392-017‑1080‑7
  • de Groot, Rol, Schrau­wen et al., Appli­ca­ti­on and repli­ca­bi­li­ty of bila­te­ral and simul­ta­neous mul­ti­ar­te­ri­al blood pres­su­re mea­su­re­ments in seden­ta­ry and phy­si­cal­ly acti­ve pro­fes­si­ons, CMR Jour­nal, 2017 https://doi.org/10.1016/j.artres.2018.10.167
  • Schu­ma­cher, Kaden, Trink­mann, Mul­ti­ple cou­pled reso­nan­ces in the human vas­cu­lar tree: refi­ning the Wes­ter­hof model of the arte­ri­al sys­tem, J Appl Phy­si­ol, 2017  https://doi.org/10.1152/japplphysiol.00405.2017
  • Kraus­haar, Dressel, Mass­mann, A novel prin­ci­pled method for the mea­su­re­ment of vas­cu­lar robust­ness unco­vers hid­den risk for pre­ma­tu­re CVD death, J Appl Phy­si­ol, 2018 https://journals.physiology.org/doi/full/10.1152/japplphysiol.00016.2018 ​​
  • Bau­er, Kraus­haar et al., Impact of Vas­cu­lar Func­tion on Maxi­mum Power Out­put in Eli­te Hand­ball Ath­le­tes, Rese­arch quar­ter­ly for exer­cise and sport, 2019 10.1080/02701367.2019.1639602
  • Fre­de­rik Trink­mann, Urs Benck, Juli­an Hal­der et al., Auto­ma­ted Non­in­va­si­ve Cen­tral Blood Pres­su­re Mea­su­re­ments by Oscil­lo­me­tric Radi­al Pul­se Wave Ana­ly­sis: Results of the MEASURE-cBP Vali­da­ti­on Stu­dies, Ame­ri­can Jour­nal of Hyper­ten­si­on 34(4) APRIL 2021 doi: 10.1093/ajh/hpaa174.